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By Mike Kocsis | 10 minutes read | Last updated: April 9, 2021 |
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  • Medically Reviewed by Dr. George Touliatos

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    If you are suffering from naturally-induced testosterone reduction or you have experienced the symptoms of low testosterone before, you may have come across Nebido injections as a possible treatment method for this condition especially when dealing with the NHS in the UK. Nebido is an injection that contains the most important hormone in the male body: testosterone. In these injections, testosterone is the active ingredient and those who take Nebido injections are doing so with the goal of using the testosterone to raise the levels of testosterone in their body.

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    How do testosterone Nebido injections work?

    The way that Nebido works is that it is injected into your body, usually into a muscle within the body. When it is injected, it is stored within the body and is gradually released over a period of time. This provides an evenly distributed effect that increases the effectiveness of the injection. Nebido is most commonly used as a treatment method for men who are having a lack of testosterone on the NHS in the UK. This could be caused by any number of factors, but testosterone replacement therapy has been found to be most effective when used in men who are experiencing low testosterone as a result of the natural aging process or have other symptoms such as hypogonadism.

    There are many ways to know if you are experiencing low testosterone, as the symptoms are well-documented. Here are some of the possible symptoms of low testosterone that might be a good indicator as to whether you have low testosterone. Here are some of the possible side effects of low testosterone:

    • Impotence
    • Infertility
    • Low sex drive
    • Fatigue
    • Depression
    • Bone density loss
    • Muscle mass loss

    If you are experiencing any combination of these symptoms, you may have low testosterone and need treatment. One of the best ways to address this condition is with testosterone replacement therapy, which has been known to help men all across the country fight the symptoms of low testosterone.

    How do I use Nebido?

    If you are settled on Nebido as a treatment method for low testosterone or a similar condition, you probably want to know more about how the treatment is administered and how it works. The main reason for the success and effectiveness of Nebido treatments resides in how it is administered.

    To start the treatment, your doctor or medical professional will administer Nebido slowly into one of the muscles in the body. This is usually done in the ventrogluteals, deltoid, or another dense muscle area. The Nebido type of injection is very strong and will last for a while, making it more convenient to use Nebido injections than some other types of TRT injections.


    The delivery method is what makes Nebido injections such an effective way to raise testosterone in the body. The reason for this is the fact that injections are the most direct route to get testosterone in the bloodstream. In a Nebido injection, you’ll find that the injection site creates a natural reservoir of testosterone that slowly disperses throughout the weeks to provide an evenly-balanced treatment that won’t fizzle out after a few days.

    With properly-administered Nebido treatments, you will only have to receive an injection every 10 to 14 weeks. This timeframe and wide period of time between two injections make it a highly desirable treatment and the reason that many people choose Nebido injections when it comes time to treat their low testosterone.

    How to inject testosterone Nebido?

    If you are curious about how to use testosterone nebido, you should know that it is a very simple process. Testosterone nebido is administered solely by injection, which is undoubtedly the most effective way to get testosterone in your bloodstream. With an injection, you can ensure that your testosterone takes a very fast effect and makes it easier for you to overcome the side effects of low testosterone.

    Your doctor or medical professional will show you the details, but you should know that testosterone nebido is very easily given with just an injection.

    Two common places you can inject testosterone nebido are illustrated below:

    testosterone nebido injection in glutes                testosterone nebido deltoid shoulder injection

    Image Source: Evolutionary

    Things to know about Nebido

    Though Nebido injections have been able to help thousands of men across the world with raising testosterone levels however it may not be the best testosterone option for you, it is simply one that primarily the NHS use, and not necessarily the best. There are some things that you still need to know before you decide on these types of injections as a treatment method for your low testosterone. Specifically, you need to know the risks, side effects, benefits, and other medical factors that go into this decision and determine whether Nebido injections are a suitable investment for you, these include:

    • Nebido formulations consist of 1000 mg testosterone undecanoate in 4ml of suspension and usually injected once every 10-14 weeks.
    • In practice patients can have a large peak and then levels drop to levels that cause symptoms of low testosterone to return by 6 weeks, which then leaves 6 weeks until the next injection of a patient feeling unwell. Some doctors give another injection at 8 weeks, but still patients report having crashed for 2 weeks and still unstable in their symptoms.
    • Patients report being more susceptible to high haematrocrit and haemoglobin when receiving Nebido vs other testosterone preparations for TRT.
    • The injection size is very large (4ml). This is injected all at once, it can be painful and also a patient must be monitored for anaphylaxis after injection.
    • In most countries Nebido has to be administered by a health care professional so patients often have to organise a clinic visit every 10-14 weeks and this can be disruptive to their lifestyle.
    • There are other types of testosterone to choose from, we primarily deal with testosterone Enanthate, Cypionate and Sustanon, which many healthcare professionals believe are better than Nebido.
    nebido vs enathate and sustanon

    Cypionate, Enanthate and Sustanon may be better than Nebido

    When to not use Nebido

    There are many medical conditions that might prevent someone from using Nebido injections. This is to protect individuals from harmful medical effects that might occur if Nebido testosterone injections are used in conjunction with other medications or are used at a time when injections might interfere with treatment for an existing condition. Here are some of the factors and characteristics that you might display that may lead to you being a bad candidate for Nebido injections as a treatment for low testosterone:

    • Allergies to testosterone or other ingredients that are included in Nebido injections
    • Any cancer that is androgen-dependent or cancer that is present in the breast or prostate
    • Have liver tumors or have had liver tumors in the past

    Additionally, Nebido injections are not intended for use in women and they are not intended for use in children or adolescents. There is no benefit in using Nebido injections for males under the age of 18. All of these people that fit within these descriptions should not use Nebido injections as a treatment for any condition.

    If you do start Nebido injections and it is decided by your doctor that you are a suitable candidate, then you will still need to monitor your health over time and keep an eye out for any side effects that might occur while you are using Nebido injections. It is important that you stay in communication with your medical professionals and you notify them if you are having any negative side effects.

    If you have had any of the following before starting your Nebido injection treatments or you experience them after, then you should immediately contact your doctor to reevaluate your treatment plan and determine if TRT is still the right option for you:

    • Epilepsy
    • Heart problems
    • Migraines
    • Sleep apnea
    • Cancer
    • Hypertension
    • Blood clotting
    • Liver disease
    • Kidney Disease

    If you are experiencing these symptoms, it could certainly affect whether you are considered a good choice for Nebido injections. Contact your medical professional immediately to learn if it is still safe for you to be taking Nebido injections and whether you can still benefit from it.

    Starting Nebido treatment

    Before you start Nebido injections, there are some steps to take with your medical team. First, your doctor will have to take a testosterone blood sample to measure the amount of testosterone and other contents in the blood. These measures will be important so that your medical team can determine whether the treatment is having the desired effect. In the beginning, your doctor may choose to give you the second injection after only 6 weeks of treatment to frontload the effects and get you started with your Nebido injections and the benefits that come with it. From there on out, you can expect injections every 10 to 14 weeks. This is done to quickly reach the desired testosterone level so that you can enter the maintenance portion of the treatment.

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    Maintaining Nebido testosterone levels

    The next stage in the Nebido injection treatment is to achieve and maintain normal testosterone levels after the initial injections. To do this, you’ll be seeing your medical professional who will be administering your treatment every 10-14 weeks for the best results. During this time, your doctor will continue to take tests and determine the amount of testosterone in the blood. They will determine if there is enough during this time and if adjustments need to be made in your dosage amount or frequency. During the maintenance stage, you should bring up any concerns or questions that you have about your treatment so that they can be addressed by your medical professional.

    Where and how to get testosterone Nebido?

    • Speak to one of our consultants about your health symptoms.
    • Undergo a full testosterone blood test to check for health issues.
    • Upon successful diagnosis of low testosterone we will offer you a variety of treatment options.
    • Depending on your preference and what we think will work best for you we may prescribe you testosterone Nebido.
    • Testosterone Nebido prescriptions will be issued and your health and testosterone levels will be monitored on an ongoing basis.
    • Symptoms and prescribed treatment of testosterone Nebido will be monitored on an ongoing basis.

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    What are the possible side effects of Nebido?

    One of the most important things you need to know when you start Nebido injections is that there are potential side effects. Being familiar with these side effects is the best way to be able to address them if they happen. There are some common side effects that are seen when using Nebido injections and others that are uncommon. We will list both here, but you should know that if you experience any side effects that you are concerned about, you should reach out to your doctor for any assistance that you may require.

    Here are some of the most common side effects that are associated with Nebido injections:

    • High red blood cell count
    • Weight gain
    • Hot flashes
    • Acne
    • Enlarged prostate
    • Irritation at the injection site


    Here are some of the lesser-common side effects that you may experience during Nebido injection treatments:

    • Allergic reactions
    • Increased appetite
    • Depression
    • Migraines
    • Fatigue
    • Prostatic disorders

    If you experience any of these symptoms and you are concerned about your health and comfort, you should contact your doctor immediately

    Testosterone Nebido dosages

    We’ve outlined dosages in another blog post, check out our guidelines in the correct testosterone nebido dosages for more information, although typically you have to inject 1000mg every 8-12 weeks.

    Testosterone Nebido costs UK

    TRT treatment packages for testosterone nebido costs between £70 and £113 per month, depending on the treatment options you go for, if you are interested in how to get testosterone nebido then contact us.

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    Nebido injections have long been one of the most successful and commonly-used treatment programs for men who are experiencing low testosterone levels. Now that you know more about Nebido injections and what the treatments entail, you can might like to speak to one of our consultants for free at Balance My Hormones to discuss your testosterone issues and potential treatment options.

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    Evidence Based Research

    This article has been researched and written based on scientific evidence and fact sheets that have then been crossed checked by our team of doctors and subject matter experts.

    References, sources and studies used alongside our own in-house research have been cited below, most of which contain external clickable links to reviewed scientific paper that contain date stamped evidence.

    Our team of healthcare experts and GMC registered doctors are licensed to UK GMC standards. We strive to provide you with the latest evidence based, researched articles that are unbiased, honest and provide you with accurate insights, statistics and helpful information on the discussed topic to ensure you gain a better understanding of the subject.

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    About the Author: Mike Kocsis

    Mike Kocsis has an MBA with a focus on healthcare administration and is an entrepreneur and medical case manager for Balance My Hormones Ltd which offers medical services in the UK and Europe. Mike has over 20 years of experience in the healthcare sector, much of that working with people who have hormone imbalances. Mike has appeared on podcasts and radio and is an expert speaker on the subject of hormone imbalance. He specialises in Testosterone Replacement Therapy (TRT) and Hormone Replacement Therapy (HRT) and has helped thousands of people suffering from hormone imbalances recover and regain control of their lives. You can follow him on LinkedIn and on the Balance My Hormones YouTube Channel.

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    Last update: April 9th, 2021

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