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What is Testosterone Cypionate & How to Get It

What is Testosterone Cypionate & How to Get It

By Mike Kocsis | 10 minutes read | Last updated: June 2, 2025   Categories:   Testosterone

Medically Reviewed by Dr. George Touliatos

Evidence Based Research

What is testosterone cypionate?

Testosterone cypionate is a synthetic version of the naturally occurring hormone testosterone, which plays a crucial role in male health and development.

It is an androgen ester, specifically formulated to replace or supplement testosterone in individuals with low levels of this essential hormone.

This prescription drug is commonly sold under the brand names Depo-Testosterone and Azmiro and is also available in its generic name.

Administered via injection, testosterone cypionate is designed to provide a slow and sustained release of testosterone into the bloodstream.

This helps maintain stable testosterone blood levels over time, reducing the frequency of injections compared to other forms of testosterone therapy.

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Is testosterone cypionate water or oil-based?

Testosterone cypionate 200 comes as an oil-based solution that is typically administered through intramuscular injection.

testosterone cypionate 200

How does testosterone cypionate injection work?

Testosterone cypionate is an ester of testosterone, specifically designed to have a prolonged release when administered intramuscularly.

The molecular structure of testosterone cypionate includes a cyclopentylpropionate ester group, which slows the release of the steroid hormone into the bloodstream.

This results in a longer concentration with time compared to other testosterone esters.

 

What is testosterone cypionate used for?

Testosterone cypionate is primarily used to manage symptoms of hypogonadism, a condition in which men have low testosterone levels. It does this by bringing their low testosterone levels back to normal.

This medication is prescribed for two types of hypogonadism, which are:

  • Primary hypogonadism: It occurs when the testes fail to produce enough testosterone. It is typically caused by genetic conditions, injury, or diseases affecting the testes themselves.
  • Secondary hypogonadism: It happens when the pituitary gland or hypothalamus fails to signal the testes to produce testosterone.

Testosterone cypionate is used for treating other issues as well, such as:

  • Delayed puberty: If puberty does not start by 14 years of age, boys may be prescribed testosterone cypionate 200. It will help promote the development of secondary sexual characteristics.
  • Other hormonal imbalances: Hormonal issues like low T can result in depression, fatigue, low libido and other symptoms. Testosterone cypionate 200 can help alleviate these symptoms.

 

Testosterone cypionate for bodybuilding

Due to testosterone cypionate’s anabolic (muscle-building) and androgenic (promoting male characteristics) effects, some athletes and bodybuilders use it to improve their performance.

However, it is not legally allowed to be used for such purposes without any medical supervision.

It is because when testosterone is administered without a proper check and balance, it can lead to serious side effects like hormonal imbalances, cardiovascular issues, and liver damage.

 

What are the benefits of testosterone cypionate 200?

Testosterone cypionate offers several benefits for those suffering from low T, including:

Increase in muscle mass and strength

One of the most significant benefits of testosterone cypionate is its ability to increase muscle and strength. Testosterone is an anabolic steroid, meaning it promotes the growth of muscle tissue.

By increasing T-levels, testosterone cypionate enhances protein synthesis within muscle cells, leading to increased muscle mass and strength.

A 2020 study concludes that taking long-term TRT can improve muscle mass in elderly men.

Improved mood and cognitive function

Low T levels have been linked to mood disorders, including depression and anxiety. T

estosterone cypionate can help alleviate these symptoms by increasing T-levels, which can improve mood and cognitive function.

Various studies have shown that TRT can lead to significant improvements in mood, energy levels, and overall quality of life.

Improved libido and sexual function

Testosterone plays a crucial role in maintaining libido and sexual function in men.

Low T levels can lead to erectile dysfunction, reduced libido and other sexual health issues.

Testosterone cypionate can help restore normal sexual function by increasing T-levels. This can lead to improved libido, better erectile function, and overall sexual satisfaction.

In a 2024 review consisting of 35 trials (5601 randomised participants), researchers noticed an improvement in sexual function in all participants who took TRT.

Increase in bone density and strength

Testosterone is essential for maintaining bone density and strength.

Low T levels can lead to decreased bone density, increasing the risk of fractures and osteoporosis.

Testosterone cypionate can help improve bone density and strength by increasing T-levels. This is particularly important for older adults and individuals with conditions that affect bone health.

This 2025 research article published in The Journal of Clinical Endocrinology & Metabolism shows that TRT improves bone mineral density and overall skeletal health in hypogonadal men.

 

What is the half-life of testosterone cypionate 200?

Testosterone cypionate’s half-life is around eight days. This means if you receive an injection of 200 mg, then after 8 days the amount of testosterone remaining in your body would be approximately 100 mg.

After another 8 days (making a total of 16 days since the initial injection), the amount would further reduce to about 50 mg.

That is why it is injected deep into muscles every two to four weeks to maintain stable blood levels and ensure continuous effectiveness of the treatment.

This dosing schedule provides a more consistent hormone level throughout the treatment period.

 

Testosterone cypionate dosages

The appropriate dosage of testosterone cypionate depends on various factors, including the patient’s age, health condition, and response to treatment.

For adult males with hypogonadism, the typical starting dosage is 50-100 mg of testosterone cypionate administered every week or 100-200 mg administered every two weeks.

The dosage may be adjusted based on the patient’s response and serum testosterone levels.

 

The truth about testosterone cypionate 200 injection

Testosterone cypionate 200 is effective in increasing testosterone levels and reducing low T symptoms. However, there are misconceptions that it can instantly increase your muscle mass and decrease low T symptoms dramatically.

The truth is, while this testosterone injection does manage low T signs, these changes occur gradually and most effectively when combined with healthy lifestyle changes.

You start noticing testosterone cypionate 200 results in weeks (or, in some cases, in months), not in days. So, be patient and consistent with your treatment regimen to truly benefit.

 

Before using testosterone cypionate 200

Before you start taking this medication, it is important to have your hormone levels properly checked. Your doctor will only prescribe it if your levels are abnormally low.

If you are already taking certain medications or have health concerns like infertility (that men may experience after starting this medication), do discuss this with your doctor.

This will help them design a TRT treatment plan that matches your needs.

 

While using testosterone cypionate 200

When you start taking testosterone cypionate 200, you will regularly have blood tests.

These will help your doctor determine how your body is responding to this treatment. They may adjust your dose to make sure it stays within a safe range.

After taking it for a few weeks, you may notice an improvement in your:

  • Mood
  • Energy levels
  • Libido
  • Lean body mass

 

After using testosterone cypionate 200

If your testosterone level stays low due to a permanent defect, you may need to take testosterone cypionate indefinitely to keep hormone levels stable.

Once you stop taking testosterone cypionate 200, your testosterone levels drop, and you will eventually start experiencing low T symptoms again. These symptoms include:

  • Low energy levels
  • Reduced sex drive
  • Erectile dysfunction
  • Increased body fat
  • Muscle mass reduction

 

How to obtain testosterone cypionate?

To get testosterone cypionate, you should first consult with a healthcare provider.

Here are the steps typically involved:

  1. Consultation: Speak to a consultant about your symptoms.
  2. Blood test: Undergo a full testosterone blood test to check your testosterone levels.
  3. Diagnosis: If diagnosed with low T or a related condition, your doctor will discuss treatment options, including testosterone cypionate.
  4. Prescription: If suitable, your doctor will prescribe testosterone cypionate.
  5. Monitoring: Your health and testosterone levels will be monitored regularly to ensure the treatment’s efficacy.

 

How to get testosterone cypionate in the UK?

In the UK, obtaining testosterone cypionate for men involves several key steps, primarily guided by medical consultation and regulatory requirements.

First, you need to consult with a healthcare provider to discuss symptoms related to low T.

Your doctor will then conduct a comprehensive evaluation, including a blood test to measure your testosterone levels and diagnose any underlying conditions like hypogonadism.

If testosterone is deemed a suitable treatment, your doctor can prescribe it.

However, it’s important to note that testosterone cypionate is not typically licensed in the UK and is often used as a secondary option when other testosterone forms are unsuitable.

You may need to source it through private clinics that offer specialised hormone therapies or obtain it via import from international suppliers.

Regular monitoring and follow-up appointments are necessary to ensure the therapy’s effectiveness and manage any potential side effects.

 

Where to buy testosterone cypionate online?

Balance My Hormones is a reputable source from where you can buy testosterone cypionate 200 in the UK. We offer a professional service for individuals looking to manage their testosterone levels.

To purchase testosterone cypionate online through Balance My Hormones, you’ll need to first undergo a consultation with one of our medical professionals.

They will assess your health needs and determine if testosterone replacement therapy is appropriate for you.

Once prescribed, you can receive testosterone cypionate directly through our trusted delivery service, ensuring convenience and confidentiality.

 

How to inject testosterone cypionate?

Testosterone cypionate is administered by injection. Testosterone injection is by far the best way to increase the amount of testosterone in your body because it goes right into the bloodstream and starts working faster as well as more effectively.

The factor that will differ from one individual to another is the dosage and frequency that you take your injections in.

These factors will depend on your age, the condition that you are trying to treat, how severe the condition is, any other medical conditions you have, and how you react to your early-stage TRT.

Here is how you can inject a testosterone cypionate injection accurately:

Where to inject testosterone cypionate?

Testosterone is an intramuscular injection, meaning it is injected into the muscle.

The most common testosterone cypionate injection sites are:

  • Thigh (Vastus Lateralis)
  • Buttocks (Gluteus Medius)
  • Deltoid (Shoulder)

Testosterone cypionate injection

Testosterone cypionate injection
Image Source: Evolutionary

What are the side effects of testosterone cypionate 200?

Like any medication, testosterone cypionate can cause adverse reactions. Common side effects of testosterone include:

  • Water retention: Increased sodium retention can lead to fluid accumulation, causing oedema.
  • Acne and oily skin: Elevated T-levels can increase sebum production, leading to acne.
  • Mood swings: Hormonal fluctuations can affect mood and emotional stability.
  • Increased blood cells: Testosterone stimulates erythropoiesis, which can lead to polycythemia.
  • Hair loss: Elevated T-levels can accelerate androgenic alopecia in genetically predisposed individuals.

More severe side effects may include:

  • Cardiovascular issues: Increased risk of hypertension, heart attack, and stroke.
  • Prostate cancer: There is an ongoing debate about the relationship between TRT and prostate cancer risk.
  • Hepatocellular carcinoma: Long-term use of anabolic steroids has been linked to liver cancer or liver disease.
  • Sleep apnea: Testosterone can exacerbate sleep apnea in some individuals.
  • Gynecomastia: Excess testosterone can be aromatised to estrogen, leading to breast tissue growth in men.

It is important to never abuse/misuse testosterone, always take it according to your prescriber’s instructions, and have follow-up sessions.

 

Who should avoid testosterone cypionate 200?

If testosterone cypionate 200 is effective for one person, it does not mean it is suitable for everyone.

Certain individuals should avoid using this medication due to its potential health risks or complications. These include:

  • Men with prostate cancer/had prostate cancer
  • Those who have or ever had a heart disease, stroke, kidney problem, diabetes, liver problem, prostate problem, breast cancer, or prostate cancer
  • Individuals with a history of blood clots
  • Men with severe sleep apnea

Taking TRT (testosterone replacement therapy) may worsen their condition.

That is why you must discuss your full medical history with your doctor to determine whether testosterone is safe for you.

 

Testosterone cypionate and drug interactions

Testosterone cypionate can interact with other drugs, leading to increased or decreased side effects.

Always inform your healthcare provider about all medications you are taking to avoid any harmful interactions. Common drug interactions:

Anticoagulants: Testosterone can enhance the effects of blood thinners, increasing the risk of bleeding.

Insulin and oral hypoglycemics: Testosterone can affect glucose metabolism, necessitating adjustments in diabetes medication.

Corticosteroids: Concurrent use with corticosteroids can exacerbate fluid retention and increase the risk of oedema.

 

What is the difference between testosterone cypionate, enanthate, and propionate?

There are several forms of injectable testosterone, including testosterone propionate and enanthate.

While all these forms aim to increase testosterone levels, they differ in their half-life (concentration over time) and dosing schedule.

The choice between these esters depends on the patient’s response and preference, as well as the prescribing doctor’s recommendation.

Testosterone cypionate: It has a longer half-life so it decreases in concentration slower than T-propionate, requiring less frequent injections.

Testosterone enanthate: The primary difference between the two lies in their ester chains; testosterone enanthate has an enanthate ester, while testosterone cypionate has a cypionate ester.

This minor difference in chemical structure results in slightly different pharmacokinetics, but both are effective for maintaining stable T-levels with less frequent dosing compared to T-propionate.

Testosterone propionate: It is a shorter-acting testosterone ester that requires more frequent injections, typically every 2 to 3 days.

This ester is preferred by some individuals who may need to adjust their testosterone levels more frequently or who may have specific reactions to longer-acting esters.

However, the need for more frequent injections can be a drawback for some patients, making testosterone cypionate or enanthate more convenient options for many.

 

Can I take clomid with testosterone cypionate?

Clomid (clomiphene citrate) is a medication people take to increase their endogenous testosterone (testosterone that the body produces naturally).

It works by stimulating the pituitary gland to release LH and FSH hormones that prompt the testes to produce testosterone.

This way, clomid increases sexual function and sperm count, which is especially beneficial for men with fertility issues (that potentially come with TRT).

Some doctors prescribe a combination of clomid with testosterone to improve fertility in men who want to conceive while on testosterone cypionate.

Combining both treatments can support the maintenance of natural testosterone production and sperm count while still providing the benefits of TRT.

However, this combination has not been well studied in research. Work with your healthcare provider to determine if it is a safe option for you.

 

More related questions

Is testosterone cypionate a steroid?

Yes, testosterone cypionate is an androgen and anabolic steroid (AAS). It is an FDA-approved medication used to treat male hypogonadism and other health conditions.

How long does it take testosterone cypionate to work?

Testosterone cypionate starts working right away, but its effects become prominent only after weeks to months.

Its initial effects, like mood changes, may be noticed within a few weeks. More significant results, like muscle growth, become more noticeable after months.

How much does 200 mg of testosterone cypionate cost?

The cost of testosterone cypionate 200 mg varies depending on the brand, supplier and whether medical consultation is included. Typically, a 10 ml multi-dose vial costs around £210. It can last for more than 4 months.

How long does testosterone cypionate stay in your system?

Testosterone cypionate has an 8-day half-life, meaning half of it will be eliminated from the body after eight days. Its traces can still be found in blood after 3 to 4 weeks of the first injection.

Does testosterone cypionate need to be refrigerated?

No, testosterone cypionate needs not to be refrigerated. Store it in a sterile place away from light at room temperature from 20° to 25°C (68° to 77°F).

Does testosterone cypionate expire?

Yes, like any other medication, testosterone cypionate also expires. It is generally printed on the vial so make sure you check the packaging before administering testosterone.

Most testosterone cypionate formulations have around a 24-month expiry date from the date of manufacture.

 

Final thought

In conclusion, testosterone cypionate is a valuable option for individuals experiencing the effects of low testosterone.

Its ability to restore normal hormone levels and alleviate symptoms makes it a significant component of hormone replacement therapy.

As with any medical treatment, ongoing monitoring and open communication with healthcare professionals are essential to optimising the benefits of testosterone cypionate and minimising potential risks.

If you want to learn more about TRT in the UK and explore your options, get in touch with Balance My Hormones.

Our specialist doctors are here to assess your symptoms, provide personalised advice, and guide you through the most effective TRT treatment options tailored to your needs.

Book Free Consultation

References

Yassin, A., Al‐Zoubi, R.M., Alzubaidi, R.T., Kamkoum, H., Zarour, A.A., Garada, K., Elaarag, M., Al‐Qudimat, A.R., Fares, Z.E. and Al‐Ansari, A.A., 2025. Testosterone and men’s health: An in‐depth exploration of their relationship. UroPrecision3(1), pp.36-46.

Tenuta, M., Hasenmajer, V., Gianfrilli, D. and Isidori, A.M., 2025. Testosterone and male bone health: a puzzle of interactions. The Journal of Clinical Endocrinology & Metabolism, p.dgaf191.

Cruickshank, M., Hudson, J., Hernández, R., Aceves-Martins, M., Quinton, R., Gillies, K., Aucott, L.S., Kennedy, C., Manson, P., Oliver, N. and Wu, F., 2024. The effects and safety of testosterone replacement therapy for men with hypogonadism: the TestES evidence synthesis and economic evaluation. Health Technology Assessment (Winchester, England)28(43), p.1.

Zitzmann, M., 2020. Testosterone, mood, behaviour and quality of life. Andrology8(6), pp.1598-1605.

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Evidence Based Research

This article has been researched and written based on scientific evidence and fact sheets that have then been crossed checked by our team of doctors and subject matter experts.

References, sources and studies used alongside our own in-house research have been cited below, most of which contain external clickable links to reviewed scientific paper that contain date stamped evidence.

Our team of healthcare experts and GMC registered doctors are licensed to UK GMC standards. We strive to provide you with the latest evidence based, researched articles that are unbiased, honest and provide you with accurate insights, statistics and helpful information on the discussed topic to ensure you gain a better understanding of the subject. You can read more about our Editorial Process by clicking here.

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About the Author: Mike Kocsis

Mike KocsisMike Kocsis has an MBA with a focus on healthcare administration and is an entrepreneur and medical case manager for Balance My Hormones which offers medical services in the UK and Europe. Mike has over 20 years of experience in the healthcare sector, much of that working with people who have hormone imbalances. Mike has appeared on podcasts and radio and is an expert speaker on the subject of hormone imbalance. He specialises in Testosterone Replacement Therapy and Hormone Replacement Therapy (HRT) and has helped thousands of people suffering from hormone imbalances recover and regain control of their lives. You can follow him on LinkedIn and on the Balance My Hormones YouTube Channel.

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Last update: June 2nd, 2025

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