Human Growth Hormone (HGH) is a small protein made by the pituitary gland and secreted into the bloodstream mainly at night whilst you sleep. HGH production is produced in the hypothalamus of the brain and in the intestinal tract and pancreas and is a complex set of hormones.
The pituitary gland will put out HGH in bursts typically when you sleep however the levels of HGH can rise when exercising or you sustain injury. Under normal conditions, more HGH is produced at night than during the day, whilst your body has time to repair and grow. This constant change in HGH levels in the blood makes it a more complex hormone to study and accurately identify whether you have a hormonal imbalance with HGH. Typically the human body will produce a rise in HGH during childhood, peaks during puberty, and declines from middle age onward.
HGH acts on many tissues throughout the body, it also stimulates the growth of cartilage and bone production. In people of all ages, HGH promotes the utilization of fat, increases protein production and changes blood sugar levels. HGH also raises levels of insulin-like growth factor-1 (IGF-1).
Ageing has a profound effect on release of HGH, described as ‘somatopause’ in these cricumstances. Studies in both men and women have shown that the intensity of HGH pulses is reduced as we age. HGH secretion declines by 50% every 7 years after age 18-25 in men.
Ageing tends to diminish the production of HGH until very little is produced. Men seem to experience a more profound reduction in HGH compared to women of a similar age. It could be that oestrogen in women has a protective effect on the rate of diminishing HGH secretion. Many men and women undertake HGH therapies for anti-ageing effects and to maintain proteins.
Balanced testosterone replacement therapy can help enhance the positive effects of improved body composition including lean body mass when combined with HGH therapy. Low levels of HGH/IGF-1 and testosterone are highly correlated to low bone density and increasing body fat and decreasing muscle mass. In fact, muscle mass can decrease by as much as 40% between the ages of 25 and 75.
Therefore, maintaining healthy HGH and testosterone levels are important for healthy ageing. As men age and hormone levels plummet they may also begin to suffer from metabolic syndrome – resulting in diabetes. Several studies have shown the link between low hormones and metabolic syndrome. This can be mitigated by maintaining healthy levels of testosterone and HGH, enabling them to work together synergistically.
Balance My Hormones helps customers restore their hormones to optimal levels through bespoke TRT and HRT treatment plans. We use modern American treatment methods and have over 25 years of experience in hormonal health which is backed up by our very own GPhC pharmacy.