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Medically Reviewed by Dr. George Touliatos
We all experience moments in life when we forget to do something that we planned earlier or forget where we placed an important item. Well, these situations may seem frustrating, but they are a normal part of life.
But when you start forgetting about things and important matters more frequently, you may have an underlying issue that needs to be addressed.
Though forgetfulness is a natural part of ageing, some experts believe that your low testosterone (low T) levels can cause or aggravate the situation.
Testosterone is the main androgen in men. It is secreted by testes and plays different roles in the body throughout life. Some of its important roles include the appearance of facial or body hair, development of the libido, increase in bone density, increase in sperm count and improvement in cognitive function.
When you become deficient in testosterone (your testosterone levels drop below normal levels of 300 nanograms/deciliter (ng/dL)), your body fails to properly execute the tasks that depend on testosterone. As a result, you may lose facial or body hair, fail to have an erection, lose bone density, experience depression, have a lack of energy, feel irritability, and experience a decline in cognitive abilities.
Low T can reduce your level of productivity and make you unable to do certain tasks that you used to enjoy. If you experience any low T symptoms, you should not sit idle. Instead, take timely action to get the issue resolved in time.
Visit your doctor and share your concerns. Tell him how you have been feeling lately. The doctor may run a physical examination like checking body hair, size of testicles, etc., before asking you to have a testosterone test.
In this test, the amount of your total testosterone (a combination of free and attached testosterone) will be checked. If it is below the normal amount, you may have low T and need a proper treatment that can help you restore testosterone levels.
Low T can occur due to a multitude of reasons. The most common reasons why you may have this issue are:
Whatever the reason may be, low T can have a negative impact on your life. Its symptoms that we have already mentioned earlier vary from one man to the other. One of these symptoms is a decline in brain health and cognitive function.
Men with low T often experience brain fog, difficulty concentrating, mood swings, depression, and anxiety. These all signs may be somehow linked to a decline in brain health.
Let’s understand the possible connection between testosterone levels and brain health through the following research work.
According to research, low T in men increases their risk of the development of Alzheimer’s disease and age-related dementia.
The research was conducted on 153 older Chinese men by the scientists at the University of Hong Kong. At the start of the research, their cognitive function was tested. 47 of the total men were reported to have mild cognitive impairment.
In a year, 10 out of 153 men developed Alzheimer’s disease. These 10 men were from the group of 47 men who were initially reported to have poor cognitive function. Their testosterone levels were also low.
In this study, researchers worked on three independent predictors of the development of Alzheimer’s disease. These predictors were low testosterone levels, high systolic pressure, and the existence of apolipoprotein E (ApoE) protein genotype.
Researchers concluded that restoring levels of testosterone may be the best way of restoring cognitive decline and improving overall mental health. For this, patients may need to have testosterone replacement therapy.
According to the researcher Scott Moffat, PhD, more research needs to be done to understand the role of testosterone clearly. It is yet unknown whether testosterone directly prevents Alzheimer’s disease or another factor, which is associated with testosterone levels, is playing this role.
If testosterone is really the cause behind the progression of Alzheimer’s disease, then the prominent benefits of testosterone replacement therapy (TRT) would overweight its risks. According to the researchers, men receiving TRT should be closely examined to make sure their testosterone levels stay normal, and no serious side effects appear.
Another possible reason behind the reduction in cognitive function due to low T might be the connection between testosterone and cortisol levels.
Cortisol is also called the stress hormone, for it is secreted in high concentration when you are under stress. We all know that our brains fail to concentrate and think properly during stress. When you have chronically high cortisol levels, you may often experience issues like lack of concentration, mental clarity, etc. so, reducing cortisol levels may help you overcome this issue.
You might be thinking about what the role of testosterone in it is? Many scientists believe that your testosterone levels drop automatically when your cortisol levels are high. So, when your blood has high cortisol constantly, it might be difficult for the body to produce sufficient testosterone.
Some experts believe that increasing the levels of testosterone may help people manage their cortisol levels and bring a balance.
If you think you forget things very frequently and it has become hard to concentrate, it is best to visit your doctor to find the underlying cause. Several things can contribute to poor cognitive function and brain health.
Your doctor will get your medical history and then conduct different tests to diagnose the real cause behind poor mental health. He will offer you treatment based on the cause of the issue. If the cause is low T, then the best possible solution might be TRT.
Testosterone replacement therapy is a treatment in which synthetic testosterone or derivatives of testosterone are used to restore the levels of testosterone in the blood. This treatment is given to people who cannot produce testosterone in the normal concentration or, in short, those who are deficient in testosterone.
Testosterone is inserted into the body through different means such as injections, medications, gels, patches, etc. You can tell your physician or therapist how you want to take testosterone, or your doctor can also guide you on which testosterone is right for you.
TRT is an effective treatment for those who have low testosterone concentration in their blood. It can help them recover their testosterone levels and start enjoying life once again.
Here are the key benefits of having TRT.
Though TRT has many benefits, there are also some risks associated with it. People who have TRT may experience the following issues.
TRT has more benefits than side effects. Learn its pros and cons in detail from the therapist to find if it is suitable for you or not.
Researchers have not yet understood the clear role of testosterone in improving cognitive health, but they believe that people who are deficient in testosterone are more likely to develop mental health issues like dementia and Alzheimer’s disease.
Therefore, getting testosterone replacement therapy might be the right solution for increasing your testosterone levels and improving brain health.
Kenny, A.M., Fabregas, G., Song, C., Biskup, B. and Bellantonio, S., 2004. Effects of testosterone on behaviour, depression, and cognitive function in older men with mild cognitive loss. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 59(1), pp.M75-M78.
Lv, W., Du, N., Liu, Y., Fan, X., Wang, Y., Jia, X., Hou, X. and Wang, B., 2016. Low testosterone level and risk of Alzheimer’s disease in the elderly men: a systematic review and meta-analysis. Molecular neurobiology, 53(4), pp.2679-2684.
https://www.sciencedaily.com/releases/2010/10/101005171202.htm
This article has been researched and written based on scientific evidence and fact sheets that have then been crossed checked by our team of doctors and subject matter experts.
References, sources and studies used alongside our own in-house research have been cited below, most of which contain external clickable links to reviewed scientific paper that contain date stamped evidence.
Our team of healthcare experts and GMC registered doctors are licensed to UK GMC standards. We strive to provide you with the latest evidence based, researched articles that are unbiased, honest and provide you with accurate insights, statistics and helpful information on the discussed topic to ensure you gain a better understanding of the subject.
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You may have low testosterone depending on the symptoms you have, please contact us to find out how we can help.
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