TRT in the UK

Hormone Replacement Therapy (HRT) and Ageing

Hormone Replacement Therapy (HRT) and Ageing

By Dr. George Touliatos | 3 minutes read | Last updated: October 17, 2021
  •   Categories:  
  • Medically Reviewed by Dr. George Touliatos

    Evidence Based Research

    The male midlife crisis and how testosterone plays its part

    To help preserve skeletal muscle and avoid muscle wasting hormone replacement therapy (HRT) can be used to support an optimal hormone environment as we age. Testosterone replacement therapy (TRT) specifically will ensure there is no catabolic effect of cortisol, which is antagonistic to androgens and testosterone in particular. After the age of 40 in men androgens typically decline and andropause commences. This is the reason men start to observe a significant loss in lean body mass, feel weaker due to muscle shrinkage and often have a reduced metabolic rate. This eventually increases the level of visceral fat, that in turn increases estrogens, which provide a negative feedback to hypothalamus for GnRH & LH production.

    Take Hormone Quiz

     

    testosterone hormone level with age

    What happens when testosterone decreases as men age

    Less muscles will eventually lead to an increase in insulin resistance, since muscles are the number one metabolic regulator in the body that burn glucose. Insulin resistance can lead to diabetes type II and dislipidemia, metabolic syndrome, cardiovacular disease. The efficiency of visceral fat oxidation becomes sluggish,with low testosterone levels. It has been estimated that SHBG elevates in elderly men and as a result Free Testosterone drops. In addition the drop in secondary androgens like DHT, DHEA can begin to affect ones mental health. Dihydroxytestosterone is a metabolite of testosterone, that improves self esteem,cognitive function and sex drive whereas DHT makes the skin of the scrotum more firm and softens epidrmis by the release of sebum, making it more elastic. Dihydroepiandrosterone released by the adrenals is an androgen with helps with immune response and is considered as the mother of all hormones.

    How HRT Helps with ageing

    Testosterone synthesizes muscle tissue by increasing possitive nitrogen balance, through assimilation of animal protein It also stimulates aldosterone release from the kidneys, a mineralcorticosteroid that retains sodium and water as a result. In this way sarcoplasm is volumized and muscles appear fuller, toned and this practically equals to greater anabolism. Contractile muscle constists seventy percent of water, nevertheless, other anabolic-anti catabolic agents can be implemented in hormonal replacement therapy. Nandrolone decaonate, known as decadurabolin, is a pharmaceutical anabolic androgenic steroid that has been extensively implemented in medical field for the past fifty years. It has the ability to reverve osteoporosis and speed up bone fracture healing by increasing calcium reabsorption in renal tubules. Nandroline can become a valuable tool to increase bone mineral density, nandrolone is also capable to improve stamina and endurance, by stimulating erythropoietin from kidneys. This was a classic indication of AAS way before EPO was manufactured. Nandrolone is a great anabolic agent, meaning it is capable of building tissues and boosting the process of anabolism. Anabolism has a plethora of benefits in quite a few medical cases such as trauma, burns, cachexia and recovery of muscle injuries. Connective tissue and muscles consist of amino acids, therefore through a diet that is rich in animal protein we can achieve superb level of healing of tissues. As muscles are strenghtend from resistance training, bones also become stronger as they are attached on to the muscles. It is well known that lifting weight in post menopausal women can help to fight against osteopenia and avoid bone fractures. Last but not least, HRT and nandrolone helps with aldosterone, that improves retention of water and lubricates synovial cavities. This can become very useful agent against arthitis and cracky joint in elbows for instance. We therefore realise the plethora of benefits provided by a single steroid, with low liver toxicity and minor effects in lipids. Nandrolone is also of low androgenicity, meaning that even women can use it under minor doses, without having the androgenic side effects of virilisation like hirsutism and acne.

    Take Hormone Quiz

    Growth Hormone and Ageing

    Growth Hormone (GH) is conidered as the foundation of youth, that works synergisticaly with testosterone against catabolic diseases. Growth hormone favors anabolism by increasing DNA synthesis of tissues, throughout its peptide insulin like growth factor, or somatomedin C. Somatotropin, known as GH, decreases with age and this is evaluated by measuring serum IGF1. Low IGF1 is linked to higher mortality rates, as high IGF1 can enhance cellular proliferation and allegedly this might speed up oncogenesis. Optimised IGF1 also known as HGH therapy has various benefits against ageing, including synthesis of collagenic fibers and connective tissue, improving skin quality, elasticity of arterial walls, joints,tendons, ligaments and articular surfaces, by the action of chondroblasts, the premature chondrocytes; cells that synthesize connective tissue. Growth hormone induces the proliferation of B & T cells in the thymus gland. GH elevates klotho protein, that is linked to the length of telomers and longevity.

    Hormone Replacement Therapy and HGH Therapy For Youth

    In summary growth hormone when combined to testosterone, DHT, DHEA and Nandrolone can become a powerful stack against aging, fragility that are association of mortality in elderly. Balance My Hormones are able to prescribe both HRT and HGH to people who have low levels of natural hormones, if you believe you are suffering from a hormone imbalance, you can take our hormone quiz or our testosterone specific ADAM low testosterone questionnaire.

    Book Free Consultation

    Was this article helpful?
    YesNo

    Evidence Based Research

    This article has been researched and written based on scientific evidence and fact sheets that have then been crossed checked by our team of doctors and subject matter experts.

    References, sources and studies used alongside our own in-house research have been cited below, most of which contain external clickable links to reviewed scientific paper that contain date stamped evidence.

    Our team of healthcare experts and GMC registered doctors are licensed to UK GMC standards. We strive to provide you with the latest evidence based, researched articles that are unbiased, honest and provide you with accurate insights, statistics and helpful information on the discussed topic to ensure you gain a better understanding of the subject. You can read more about our Editorial Process by clicking here.

    We value your feedback on our articles, if you have a well-researched paper you would like to share with us please contact us.

    Quick Low Testosterone Test

    If you know your total testosterone reading from a previous blood test input the results to the left above to see if your testosterone levels are normal.

    Check your testosterone

    Sex:
    Age:
    Tick all that apply:


    I have the following symptoms:

    Testosterone conversion tool
    Order testosterone blood tests

    Low Testosterone Levels

    You may have low testosterone depending on the symptoms you have, please contact us to find out how we can help.

    Take our ADAMS low testosterone questionnaire.

    Please Retry

    The Total Testosterone Level You Entered Is Incorrect. Figure Must be in nmol/L you can use our converter here.

    Take our ADAMS low testosterone questionnaire.

    Normal Testosterone Levels

    Your testosterone levels appear to be in the normal range.

    Take our ADAMS low testosterone questionnaire.

    LOOKING GOOD!

    You must be over 38, have had your ovaries removed or have suffered with premature menopause to warrant further hormone tests.

    Take our ADAMS low testosterone questionnaire.

    Further investigation needed

    Please contact us to discuss your hormones, we need your total testosterone levels to validate your hormone deficiency. You can order a blood test here.

    Take our ADAMS low testosterone questionnaire.

    Low Testosterone Levels

    You may have low testosterone depending on the symptoms you have, please contact us to find out how we can help.

    Take our ADAMS low testosterone questionnaire.

    High Testosterone Levels

    You appear to have higher than normal testosterone levels, please contact us for further investigation.

    Take our ADAMS low testosterone questionnaire.

    Normal Testosterone Levels

    You appear to have normal testosterone levels. Contact us if you have any concerns.

    Take our ADAMS low testosterone questionnaire.

    About the Author: Dr. George Touliatos

    Dr. George TouliatosDr. George Touliatos is the EU Medical Director for Balance My Hormones. He is a physician who specialises in biopathology and is a former competitive bodybuilder and light heavy weight champion (2000, 2009, 2010, 2013). He is an expert in medical prevention and harm reduction regarding PEDs use in sports and HRT/TRT in men. He has contributed to the American Muscular Development magazine (2019), and extensively developed articles on steroid abuse and TRT, you can view his latest articles here https://muckrack.com/george-touliatos/articles. He has his own weekly show on MD TV, known as ‘Ask Dr. Testosterone’, and has participated in several seminars across Greece and Cyprus, numerous TV and radio appearances, interviews in newspapers and websites.Professional Memberships and Achievements: Competitive bodybuilder ten times & national champion twice (2000, 2009, 2010, 2013).Medical associate of Anabolics 11th Edition (2017).Contributing medical author of the American Muscular Development Magazine (2019).Actively runs ‘Ask Dr. Testosterone’ podcast.Contributing author for Anabolic.org (2015-2019).Contributing author for Steroidabuse.com (2019).Tutor for ALS Academy Cyprus and Peakperformance.gr Academy in Greece (2015-2022).Scientific associate for Panatta company (2022).Author of five Greek books, five English & one Italian in bodybuilding (2012, 2013, 2015, 2017, 2018, 2020, 2021, 2023,2024).Appeared on numerous radio/talk shows such as Balance My Hormones Youtube, Super Human Radio of Kentucky, RXMUSCLE and Generation Iron.Medical AssociationMedical Association of Athens – No. 49442EducationMD – Athens School of Medicine Residency – Biopathology, Athens School of Medicine

    Learn More About Us

    Last update: October 17th, 2021
    Hormone Imbalance: Causes, Symptoms and Treatment
    Hormone Imbalance: Causes, Symptoms and Treatment
    26 March, 2024, by Mike Kocsis

    Hormones are small chemical messengers that perform many big roles in the body. To ensure optimal functioning, they must remain balanced within the body. Having too much or too little of a hormone can disrupt normal body functioning, leading to a variety of symptoms and health issues. Hormone imbalance refers to a condition in which […]

    Read Article
    Do Women Have More Oestrogen Than Testosterone?
    Do Women Have More Oestrogen Than Testosterone?
    13 March, 2024, by Mike Kocsis

    Both oestrogen and testosterone are primary sex hormones that play many crucial roles in the body. Testosterone is mainly associated with male physiology, while oestrogen is predominantly found in females. However, these hormones exist in both sexes, albeit in different concentrations. Proper balance between these hormones is essential for the overall well-being of a person. […]

    Read Article
    The Link Between Female Hair Loss and Hormones
    The Link Between Female Hair Loss and Hormones
    28 February, 2024, by Mike Kocsis

    If you are shedding more than 100 hairs daily and have bald spots, you probably have hair loss and need to see a doctor as soon as possible. There are different causes of female hair loss, and one of them is hormonal imbalance. In this article, you will learn about female hair loss and how […]

    Read Article

    Get In Touch



    File(s) size limit is 20MB.

    Get Started Today
    Evidence based
    research backed
    hormone optimization

    Balance My Hormones helps customers restore their hormones to optimal levels through bespoke TRT and HRT treatment plans. We use modern American treatment methods and have over 25 years of experience in hormonal health which is backed up by our very own GPhC pharmacy.

    jQuery('.faq-item h4 a').click(function(e){var i=jQuery(this).attr("data-id");jQuery('.faq-item .answer').hide();jQuery('#a-'+i).toggle();return!1});jQuery('.fulldbtn').click(function(){var elem='#'+jQuery(this).closest('.testbigbox').attr('id')+' .fulldetails';jQuery(elem).toggle("slow");return!1});jQuery('.mcheck').click(function(){var id=jQuery(this).attr('id');var other='';if(id=='finger'){other='vene'}else{other='finger'} if(jQuery('#'+id).is(':checked')){jQuery('.'+id).show()}else{jQuery('.'+id).not('.'+other).hide()}});jQuery('.redi').click(function(){var cnt='#'+jQuery(this).closest('.testbigbox').attr('id');var url=jQuery(cnt+' .dropdownupdate').find(':selected').data('link');window.location.assign(url);return!1});jQuery('.dropdownupdate').on('change',function(){var price=jQuery(this).find(':selected').data('price');var price_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .price';jQuery(price_container).html('Special Price: '+price);var oldprice=jQuery(this).find(':selected').data('oldprice');var oldprice_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .oldprice';jQuery(oldprice_container).html('Normal Price: '+oldprice+'');var link=jQuery(this).find(':selected').data('link');var link_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' a.orderbtn';jQuery(link_container).attr('href',link);var lefttitle=jQuery(this).find(':selected').data('lefttitle');var lefttitle_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' h2.left_title';jQuery(lefttitle_container).text(lefttitle);var lefttext=jQuery(this).find(':selected').data('lefttext');var lefttext_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .left_text';jQuery(lefttext_container).html(lefttext);var boxtitle=jQuery(this).find(':selected').data('boxtitle');var boxtitle_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .tbhead';jQuery(boxtitle_container).text(boxtitle);var boxtext=jQuery(this).find(':selected').data('boxtext');var boxtext_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .boxtext';jQuery(boxtext_container).html(boxtext);var fdttitle=jQuery(this).find(':selected').data('fdtitle');var fdttitle_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .fulldtitle';jQuery(fdttitle_container).html(fdttitle);var fulld=jQuery(this).find(':selected').data('fulldetails');var fulld_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .fulldetailscnt';jQuery(fulld_container).html(fulld);var coup=jQuery(this).find(':selected').data('coupon');var coup_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .coupon';jQuery(coup_container).html(coup);var im=jQuery(this).find(':selected').data('image');var im_container='#'+jQuery(this).closest('.testbigbox').attr('id')+' .imgcontainer img';jQuery(im_container).attr("src",im)});jQuery('.lwptoc_item a').addClass('border');jQuery('.lwptoc_item_label').css('border-bottom','2px #1d2463 solid !important');jQuery('.menu-toggle ').click(function(){var close='';var open='';if(jQuery('#menu-cnt').css('display')=='none'){jQuery('#menu-cnt').show();jQuery('.menu-toggle ').html(close)}else{jQuery('#menu-cnt').hide();jQuery('.menu-toggle ').html(open);jQuery("li.menu-item-has-children").removeClass('open')} return!1});jQuery("#videomodal").click(function(){jQuery("#myModal iframe").attr("src",'https://www.youtube.com/embed/IzmhteD7NWw');jQuery('#myModal').css('display','flex');return!1});jQuery("#videomodalquiz").click(function(){jQuery("#myModal iframe").attr("src",'https://www.youtube.com/embed/V3j482RtaQw');jQuery('#myModal').css('display','flex');return!1});function closemyModal(){document.getElementById('myModal').style.display='none';jQuery("#myModal iframe").attr("src",'')} jQuery("#ytbutton").click(function(){jQuery("#ytModal iframe").attr("src",'https://www.youtube.com/embed/MiGUJHnq1ZE');jQuery('#ytModal').css('display','flex');return!1});jQuery(".stbt").click(function(){var name=jQuery(this).attr("data-name");var bio=jQuery(this).attr("data-bio");var img=jQuery(this).attr("data-img");jQuery('#staffname').text(name);jQuery('#staffbio').text(bio);jQuery('#staffimg').attr('src',img);jQuery('#staffModal').css('display','flex');return!1});function openytmodal(){jQuery("#ytModal iframe").attr("src",'https://www.youtube.com/embed/MiGUJHnq1ZE');jQuery('#ytModal').css('display','flex');return!1} function closeytModal(){document.getElementById('ytModal').style.display='none';jQuery("#ytModal iframe").attr("src",'')} function closenoticeModal(){document.getElementById('noticeModal').style.display='none';document.cookie='notice=promos;max-age=259200000000;path=/'} function closestaffModal(){document.getElementById('staffModal').style.display='none'} function getCookie(cname){let name=cname+"=";let decodedCookie=decodeURIComponent(document.cookie);let ca=decodedCookie.split(';');for(let i=0;i992){headerHeight+=40}else if($(window).width()>1199){headerHeight+=60} $(window).scroll(function(){var scrolled=$(document).scrollTop();if(scrolled>headerHeight){$('#header').addClass('off-canvas')}else{$('#header').removeClass('off-canvas')} if(scrolled>scroll){$('#header').removeClass('fixed');if(window.matchMedia("only screen and (max-width: 760px)").matches){}}else{$('#header').addClass('fixed')} scroll=$(document).scrollTop()})})})(jQuery);jQuery.fn.outerhtml=function(){return(this[0])?this[0].outerHTML:''};jQuery(function(){let isMobile=window.matchMedia("only screen and (max-width: 760px)").matches;if(isMobile){jQuery("li.menu-item-has-children a").append('');jQuery("li#menu-item-292 ul").prepend('
  • About Us
  • ');jQuery("li#menu-item-297 ul").prepend('
  • Services Overview
  • ');jQuery("li#menu-item-7259 ul").prepend('
  • Blood Testing Overview
  • ');jQuery('#menu-primary-menu > li').click(function(e){var jQueryel=jQuery('ul',this);jQuery('#menu-primary-menu > li > ul').not(jQueryel).slideUp();jQueryel.stop(!0,!0).slideToggle(400);if(jQueryel.html()!=undefined){return!1}});jQuery('#menu-primary-menu > li > ul > li').click(function(e){e.stopPropagation()});jQuery("li.menu-item-has-children").click(function(){jQuery("li.menu-item-has-children").removeClass('open');jQuery(this).addClass('open')});const target=document.querySelector('#menu-primary-menu') document.addEventListener('click',(event)=>{const withinBoundaries=event.composedPath().includes(target) var open='';if(!withinBoundaries){jQuery('#menu-cnt').hide();jQuery('.menu-toggle ').html(open);jQuery("li.menu-item-has-children").removeClass('open')}}) var temp=jQuery('#wide1col1').html();jQuery('#wide1col1').html(jQuery('#wide1col2').html());jQuery('#wide1col2').html(temp);var temp=jQuery('#wide3col1').html();jQuery('#wide3col1').html(jQuery('#wide3col2').html());jQuery('#wide3col2').html(temp);jQuery("#menu-item-291").append('
  • Login
  • ');var temp=jQuery('.fulldbtn').outerhtml();jQuery('.fulldbtn').remove();jQuery(".newtestbox").append(temp);jQuery('.fulldbtn').click(function(){var elem='#'+jQuery(this).closest('.testbigbox').attr('id')+' .fulldetails';jQuery(elem).toggle("slow");return!1})}})